Exemestane – Quick Facts & How to Use It

If you’ve been told to take exemexane (yes, the spelling matters – it’s exemestane), you probably have questions about what it actually does. In plain terms, exemestane is an aromatase inhibitor that blocks estrogen production in post‑menopausal women. Lower estrogen levels can slow down or stop the growth of certain breast cancers that need hormone signals to thrive.

Most people start using exemestane after completing a few years of tamoxifen or as a follow‑up treatment when cancer returns. It’s taken once a day, usually at night, and you don’t have to take it with food. The pill looks like any other small tablet, so there’s no need for injections or complicated schedules.

When and Why Doctors Prescribe Exemestane

Doctors typically recommend exemestane for hormone‑positive (ER+) breast cancer that has spread to the bone or other parts of the body after menopause. It works well when the cancer is no longer responding to tamoxifen, another common drug. Because it targets estrogen production rather than blocking its effects, some patients experience fewer hot flashes compared with other treatments.

The drug is also used off‑label for conditions like gynecomastia in men or severe estrogen excess, but those uses are less common and should only happen under strict medical supervision.

Dosage, Side Effects and What to Watch For

The standard dose is 25 mg taken orally once daily. Doctors may adjust the amount if you have liver problems or severe side effects. It’s important to keep a consistent schedule – skipping days can let estrogen bounce back and reduce effectiveness.

Common side effects include joint or muscle aches, mild nausea, and occasional fatigue. About one‑third of users notice bone thinning over long‑term use, so doctors often recommend calcium and vitamin D supplements, plus periodic bone density scans.

If you experience sudden swelling in your legs, severe headache, chest pain, or signs of an allergic reaction (rash, itching, trouble breathing), call your doctor right away. Those symptoms are rare but require immediate attention.

Because exemestane is a prescription drug, buying it online can be risky. Look for pharmacies that require a valid prescription, display clear contact information, and have a licensed pharmacist available to answer questions. Avoid sites that promise “no prescription needed” – they’re often selling counterfeit pills that could do more harm than good.

When you receive your medication, check the packaging for a lot number, expiration date, and tamper‑evidence seal. Store it at room temperature away from moisture and heat; a bathroom cabinet is usually fine.

Finally, keep an open line with your oncologist. Regular blood tests help monitor liver function and cholesterol levels, which can shift while on exemestane. If anything feels off, don’t wait – reach out early to adjust the plan.

Exemestane and Body Image: Practical Tips to Cope With Physical Changes
26 August 2025

Exemestane and Body Image: Practical Tips to Cope With Physical Changes

On exemestane and struggling with body image? Learn what changes to expect and practical ways to cope, from clothes and skincare to movement, intimacy, and support.

Read More